Dott.ssa Roberta Pica

ATTIVITA' SVOLTE NEGLI ULTIMI 15 ANNI:
1) RESPONSABILE ORGANIZZAZIONE CENTRO PER LE MALATTIE INFIAMMATORIE CRONICHE INTESTINALI Ospedale Sandro Pertini Roma
2) VISITE GASTROENTEROLOGICHE: PER PAZIENTI AMBULATORIALI E PER PAZIENTI AFFERENTI ALL’AMBULATORIO M.I.C.I.
3) RESPONSABILE PRESCRIZIONE E SOMMINISTRAZIONE IN DAY HOSPITAL DEI FARMACI BIOLOGICI PER LE M.I.C.I.
4) REPERIBILITÀ PER LE URGENZE ENDOSCOPICHE H245) CONSULENZE PER ENDOSCOPIA INTERVENTISTICA
6) CONSULENZE SPECIALISTICHE GASTROENTEROLOGICHE
7) ATTIVITÀ ASSISTENZIALE NEL DIPARTIMENTO MEDICO (REPARTI DI MEDICINA GENERALE 1 E 2, ONCOLOGIA, PNEUMOLOGIA, GASTROENTEROLOGIA), CON ATTIVITÀ DI REPARTO ORDINARIO DI GASTROENTEROLOGIA E CON SERVIZI DI GUARDIA INTER-DIPARTIMENTALI
8) ATTIVITÀ (PRIMO OPERATORE) ENDOSCOPICA DIGESTIVA DIAGNOSTICA
COLONSCOPIE, GASTROSCOPIE E CPRE
9)ATTIVITÀ (PRIMO OPERATORE) ENDOSCOPICA DIGESTIVA OPERATIVA
POLIPECTOMIA CON ANSA DIATERMICA, MUCOSECTOMIE, ESD, DILATAZIONI ESOFAGEE E CARDIALI, DILATAZIONI COLON, COAGULAZIONE CON ARGON PLASMA, EMOSTASI CON SCLEROTERAPIA INIETTIVA E CON TERAPIA MECCANICA, RIMOZIONE CORPI ESTRANEI, POSIZIONAMENTO PROTESI ENTERALI, PEG
10) ATTIVITÀ (PRIMO OPERATORE) ENDOSCOPICA BILIO-PANCREATICA
CPRE- (SFINTEROTOMIA, RIMOZIONE DI CALCOLI, POSIZIONAMENTO PROTESI BILIARI)

PUBBLICAZIONI DELLA DOTT:SSA ROBERTA PICA
N. 53 LAVORI IN EXTENSO (SULLE MAGGIORI RIVISTE NAZIONALI ED INTERNAZIONALI tutte con IF)


1. Daperno M, Comberlato M, Bossa F, Armuzzi A, Biancone L, Bonanomi AG, Cosintino R, Lombardi G, Mangiarotti R, Papa A, Pica R, Grassano L, Pagana G, D'Incà R, Orlando A, Rizzello F; Training Programs on Endoscopic Scoring Systems for Inflammatory Bowel Disease Lead to a Significant Increase in Interobserver Agreement Among Community Gastroenterologists. IGIBDEndo Group. J Crohns Colitis. 2017 May 1;11(5):556-5612. Biancone L, Annese V, Ardizzone S, Armuzzi A, Calabrese E, Caprioli F, Castiglione F, Comberlato M, Cottone M, Danese S, Daperno M, D'Incà R, Frieri G, Fries W, Gionchetti P, Kohn A, Latella G, Milla M, Orlando A, Papi C, Petruzziello C, Riegler G, Rizzello F, Saibeni S, Scribano ML, Vecchi M, Vernia P, Meucci G, Rugge M. Collaborators (24) Aratari A, Bossa F, Cappello M, Cassinotti A, Chiriatti A, Fiorino G, Formica V, Guidi L, Losco A, Mocciaro F, Onali S, Pastorelli L, Pica R, Principi M, Renna S, Ricci C, Rispo A, Rogai F, Sarmati L, Scaldaferri F, Spina L, Tambasco R, Testa A, Viscido A. “Safety of treatments for inflammatory bowel disease: Clinical practice guidelines of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD).” Dig Liver Dis. 2017 Apr;49(4):338-3583. Zippi M, De Toma G, Minervini G, Cassieri C, Pica R, Colarusso D, Stock S, Crispino P. “Desmoplasia influenced recurrence of disease and mortality in stage III colorectal cancer within five years after surgery and adjuvant therapy.” Saudi J Gastroenterol. 2017 Jan-Feb;23(1):39-444. Daperno M, Comberlato M, Bossa F, Armuzzi A, Biancone L, Bonanomi AG, Cosintino R, Lombardi G, Mangiarotti R, Papa A, Pica R, Grassano L, Pagana G, D'Incà R, Orlando A, Rizzello F; IGIBDEndo Group. “Training Programs on Endoscopic Scoring Systems for Inflammatory Bowel Disease Lead to a Significant Increase in Interobserver Agreement Among Community Gastroenterologists.” J Crohns Colitis. 2016 Oct 4.
5. Cassieri C, Pica R, Avallone EV, Zippi M, Crispino P, De Nitto D, Paoluzi P, Brandimarte G, Lecca PG, Elisei W, Picchio M, Tursi A. "Prevalence of Colonic Diverticulosis in Patients Affected by Ulcerative Colitis: A Prospective Study.” J Clin Gastroenterol. 2016 Oct;50 Suppl 1:S33-56. D'Ambrosio A, Cossu A, Amendola A, Zandri A, Butera A, Sanchez M, Biffoni M, Pronio A, Montesani C, Kohn A, Pica R, Boirivant M. “Lamina Propria CD4+LAP+ Regulatory T Cells Are Increased in Active Ulcerative Colitis but Show Increased IL-17 Expression and Reduced Suppressor Activity.” J Crohns Colitis. 2016 Mar;10(3):346-537. Pica R, Cassieri C, Cocco A, Zippi M, Marcheggiano A, De Nitto D, Avallone EV, Crispino P, Occhigrossi G, Paoluzi P. A randomized trial comparing 4.8 vs. 2.4 g/day of oral mesalazine for maintenance of remission in ulcerative colitis. Dig Liver Dis. 2015 Nov;47(11):933-78. Crispino P, Pica R, Unim H, Rivera M, Cassieri C, Zippi M, Paoluzi P. “Efficacy of mesalazine or beclomethasone dipropionate enema or their combination in patients with distal active ulcerative colitis.” Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2830-79. Monteleone G, Neurath MF, Ardizzone S, Di Sabatino A, Fantini MC, Castiglione F, Scribano ML, Armuzzi A, Caprioli F, Sturniolo GC, Rogai F, Vecchi M, Atreya R, Bossa F, Onali S, Fichera M, Corazza GR, Biancone L, Savarino V, Pica R, Orlando A, Pallone F. ”Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.” N Engl J Med. 2015 Mar 19;372(12):1104-1310. Zippi M, Corrado C, Pica R, Avallone EV, Cassieri C, De Nitto D, Paoluzi P, Vernia P. ”Extraintestinal manifestations in a large series of Italian inflammatory bowel disease patients.” World J Gastroenterol. 2014 Dec 14;20(46):17463-711. Zippi M, Traversa G, Pica R, De Felici I, Cassieri C, Marzano C, Occhigrossi G, Paoluzi P. “Efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) performed in patients with Periampullary duodenal diverticula (PAD).” Clin Ter. 2014;165(4):e291-412. Daperno M, Comberlato M, Bossa F, Biancone L, Bonanomi AG, Cassinotti A, Cosintino R, Lombardi G, Mangiarotti R, Papa A, Pica R, Rizzello F, D'Incà R, Orlando A. “Inter-observer agreement in endoscopic scoring systems: preliminary report of an ongoing study from the Italian Group for Inflammatory Bowel Disease (IG-IBD).” Dig Liver Dis. 2014 Nov;46(11):969-7313. Zippi M, Bruni A, Scevola G, Pica R, Cassieri C, Marzano C, Paoluzi P. “Large symptomatic simple hepatic cyst with gastric compression treated with percutaneous drainage.” Clin Ter. 2014;165(2):e170-314. Pica R, Cassieri C, Pronio AM, Zippi M, Avallone EV, Montesani C, Occhigrossi G, Paoluzi P. “Quality of life in ulcerative colitis patients treated medically versus patients undergoing surgery.” Eur Rev Med Pharmacol Sci. 2014;18(5):693-815. Zippi M, Pica R, Marzano C, Cassieri C, Avallone EV, Traversa G. “Benign pneumoperitoneum after percutaneous endoscopic gastrostomy (PEG) feeding tube placement: do not be afraid!” Clin Ter. 2014;165(1):e76-816. Avallone EV, Cassieri C, Zippi M, Pica R, Marcheggiano A, Vernia P, Corazziari ES, Paoluzi P. “Patient with chest pain refractory to proton pump inhibitor: report of a case of eosinophilic esophagitis.” Clin Ter. 2014;165(1):e70-217. Avallone EV, Pica R, Cassieri C, Zippi M, Paoluzi P, Vernia P. “Azathioprine treatment in inflammatory bowel disease patients: type and time of onset of side effects.” Eur Rev Med Pharmacol Sci. 2014;18(2):165-7018. Zippi M, Traversa G, Bruni A, Pica R, Occhigrossi G, Scevola G. “Gastric Dieulafoy's lesion successfully treated by "adjuvant" arterial embolization and endoscopic clipping.” Clin Ter. 2013;164(6):e511-319. Zippi M, Cassieri C, Avallone EV, Pica R. “Infliximab for the treatment of pouchitis.” World J Clin Cases. 2013 Sep 16;1(6):191-620. Zippi M, Pica R, De Nitto D, Paoluzi P. “Biological therapy for dermatological manifestations of inflammatory bowel disease.” World J Clin Cases. 2013 May 16;1(2):74-821. Zippi M, Pica R, Scialpi R, Cassieri C, Avallone EV, Occhigrossi G. “Schwannoma of the rectum: A case report and literature review.” World J Clin Cases. 2013 Apr 16;1(1):49-5122. Zippi M, De Felici I, Pica R, Traversa G, Occhigrossi G. “Endoscopic papillary balloon dilation for difficult common bile duct stones: Our experience.” World J Clin Cases. 2013 Apr 16;1(1):19-2423. Zippi M, De Felici I, Pica R, Occhigrossi G, Traversa G. “Comparison of endoscopic retrograde cholangiopancreatography between elderly and younger patients for common bile duct stones.” Clin Ter. 2013;164(5):e353-824. Picarelli A, Di Tola M, Borghini R, Isonne C, Saponara A, Marino M, Casale R, Tiberti A, Pica R, Donato G, Frieri G, Corazziari E. “Colonic involvement in celiac disease and possible implications of the sigmoid mucosa organ culture in its diagnosis.” J Clin Immunol. 2013 Oct;33(7):1250-625. Zippi M, De Felici I, Pica R, Agus MA, Solinas A, Occhigrossi G, Traversa G. “Self-expandable metal stent placement for treatment of severe sphincterotomy bleeding.” Clin Ter. 2013;164(1):e27-926. Zippi M, Traversa G, Cocco A, Pica R, Cassieri C, Avallone EV, Occhigrossi G. “Use of argon plasma coagulation in digestive endoscopy: a concise review.” Clin Ter. 2012 Nov;163(6):1435-4027. Zippi M, Pica R, Scialpi R, Paoluzi P, Occhigrossi G. “Simultaneous primary gastric and duodenal MALT lymphoma presenting with gastrointestinal bleeding.” Clin Ter. 2012 Jul;163(4):e165-728. Zippi M, Traversa G, Pica R, Occhigrossi G. “Hematemesis from esophageal varices associated with esophageal perforation: sclerotherapy and endoscopic clipping.” Eur Rev Med Pharmacol Sci. 2012 May;16(5):704-629. Zippi M, Traversa G, De Felici I, Febbraro I, Mattei E, Pica R, Occhigrossi G. “Endoscopic therapy with balloon dilatation in patients with colonic post anastomotic strictures. Personal experience.” Clin Ter. 2011;162(6):539-42.
30. Bertomoro P, Renna S, Cottone M, Riegler G, Bossa F, Giglio L, Pastorelli L, Papi C, Castiglione F, Angelucci E, Pica R, Di Paolo MC, D'Incà R. “Regional variations in the use of complementary and alternative medicines (CAM) for inflammatory bowel disease patients in Italy: an IG-IBD study.” J Crohns Colitis. 2010 Sep;4(3):291-30031. Crispino P, Alò PL, Rivera M, Barillà D, Nardi F, Mariotti M, Giancarlo Z, Botti C, Pica R, Cassieri C, Unim H, Paoluzi P. “Evaluation of fatty acid synthase expression in oesophageal mucosa of patients with oesophagitis, Barrett's oesophagus and adenocarcinoma.” J Cancer Res Clin Oncol. 2009 Nov;135(11):1533-4132. Cesarini M, Angelucci E, Rivera M, Pica R, Paoluzi P, Vernia P, Corazziari ES. “Thyroid disorders and inflammatory bowel diseases: retrospective evaluation of 909 patients from an Italian Referral Center.” Inflamm Bowel Dis. 2010 Feb;16(2):186-733. Crispino P, De Toma G, Ciardi A, Bella A, Rivera M, Cavallaro G, Polistena A, Fornari F, Unim H, Pica R, Cassieri C, Mingazzini PL, Paoluzi P. “Role of desmoplasia in recurrence of stage II colorectal cancer within five years after surgery and therapeutic implication.” Cancer Invest. 2008 May;26(4):419-2534. Zippi M, Febbraro I, De Felici I, Mattei E, Pica R, Traversa G, Occhigrossi G. ”Foreign bodies in the upper gastrointestinal tract. Personal experience.” Clin Ter. 2007 Jul-Aug;158(4):291-535. Paoluzi P, Iacopini F, Crispino P, Nardi F, Bella A, Rivera M, Rossi P, Gurnari M, Caracciolo F, Zippi M, Pica R. “2-week triple therapy for Helicobacter pylori infection is better than 1-week in clinical practice: a large prospective single-center randomized study.” Helicobacter. 2006 Dec;11(6):562-836. Crispino P, Pica R, Angelucci E, Consolazio A, Rivera M, Cassieri C, Paoluzi P. “Hematological malignancies in chronic inflammatory bowel diseases: report of five cases and review of the literature.” Int J Colorectal Dis. 2007 May;22(5):553-837. Crispino P, Habib FI, Badiali D, Pica R, Iacopini F, Bella A, Cassieri C, Anzini F, Paoluzi P. “Colorectal motor and sensitivity features in patients affected by ulcerative proctitis with constipation: a radiological and manometric controlled study.” Inflamm Bowel Dis. 2006 Aug;12(8):712-838. Zippi M, Traversa G, Masini A, De Felici I, Febbraro I, Mattei E, Pica R, Bertoldi I, Occhigrossi G. “Placement of two overlapping uncovered metallic stents for malignant gastric outlet and duodenal obstruction due to colon cancer.” Dig Liver Dis. 2006 Aug;38(8):612-439. Zippi M, Colaiacomo MC, Marcheggiano A, Pica R, Paoluzi P, Iaiani G, Caprilli R, Maccioni F. “Mesenteric adenitis caused by Yersinia pseudotubercolosis in a patient subsequently diagnosed with Crohn's disease of the terminal ileum.” World J Gastroenterol. 2006 Jun 28;12(24):3933-540. Consolazio A, Alò PL, Rivera M, Iacopini F, Paoluzi OA, Crispino P, Pica R, Paoluzi P. “Overexpression of fatty acid synthase in ulcerative colitis.” Am J Clin Pathol. 2006 Jul;126(1):113-841. Crispino P, Iacopini F, Pica R, Consolazio A, Bella A, Cassieri C, Nardi F, Paoluzi P. “Beta-lactamase inhibition with clavulanic acid supplementing standard amoxycillin-based triple therapy does not increase Helicobacter pylori eradication rate.” Dig Liver Dis. 2005 Nov;37(11):826-3142. Iacopini F, Crispino P, Paoluzi OA, Consolazio A, Pica R, Rivera M, Palladini D, Nardi F, Paoluzi P. “One-week once-daily triple therapy with esomeprazole, levofloxacin and azithromycin compared to a standard therapy for Helicobacter pylori eradication.” Dig Liver Dis. 2005 Aug;37(8):571-643. Paoluzi OA, Iacopini F, Pica R, Crispino P, Marcheggiano A, Consolazio A, Rivera M, Paoluzi P. “Comparison of two different daily dosages (2.4 vs. 1.2 g) of oral mesalazine in maintenance of remission in ulcerative colitis patients: 1-year follow-up study.” Aliment Pharmacol Ther. 2005 May 1;21(9):1111-944. Pica R, Paoluzi OA, Iacopini F, Marcheggiano A, Crispino P, Rivera M, Bella A, Consolazio A, Paoluzi P. “Oral mesalazine (5-ASA) treatment may protect against proximal extension of mucosal inflammation in ulcerative proctitis.” Inflamm Bowel Dis. 2004 Nov;10(6):731-645. Di Tola M, Sabbatella L, Anania MC, Viscido A, Caprilli R, Pica R, Paoluzi P, Picarelli A. “Anti-tissue transglutaminase antibodies in inflammatory bowel disease: new evidence.” Clin Chem Lab Med. 2004;42(10):1092-746. Paoluzi OA, Pica R, Iacopini F, Paoluzi P. “Low-dose methotrexate in ulcerative colitis: still a matter of debate.” Eur J Gastroenterol Hepatol. 2004 Oct;16(10):1071-2; author reply 107247. Paoluzi OA, Crispino P, Amantea A, Pica R, Iacopini F, Consolazio A, Di Palma V, Rivera M, Paoluzi P. “Diffuse febrile dermatosis in a patient with active ulcerative colitis under treatment with steroids and azathioprine: a case of Sweet's syndrome. Case report and review of literature.” Dig Liver Dis. 2004 May;36(5):361-648. Iacopini F, Consolazio A, Bosco D, Marcheggiano A, Bella A, Pica R, Paoluzi OA, Crispino P, Rivera M, Mottolese M, Nardi F, Paoluzi P. ”Oxidative damage of the gastric mucosa in Helicobacter pylori positive chronic atrophic and nonatrophic gastritis, before and after eradication.” Helicobacter. 2003;8(5):503-1249. Paoluzi P, D'Albasio G, Pera A, Bianchi Porro G, Paoluzi OA, Pica R, Cottone M, Miglioli M, Prantera C, Sturniolo G, Ardizzone S. “Oral and topical 5-aminosalicylic acid (mesalazine) in inducing and maintaining remission in mild-moderate relapse of ulcerative colitis: one-year randomised multicentre trial.” Dig Liver Dis. 2002 Nov;34(11):787-9350. Paoluzi OA, Pica R, Marcheggiano A, Crispino P, Iacopini F, Iannoni C, Rivera M, Paoluzi P. “Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission.” Aliment Pharmacol Ther. 2002 Oct;16(10):1751-951. Di Paolo MC, Paoluzi OA, Pica R, Iacopini F, Crispino P, Rivera M, Spera G, Paoluzi P. “Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.” Dig Liver Dis. 2001 Oct;33(7):563-952. Paoluzi OA, Rossi P, Montesano C, Bernardi S, Carnieri E, Marchione OP, Nardi F, Iacopini F, Pica R, Paoluzi P. “Discrepancy between polymerase chain reaction assay and Western blot analysis in the assessment of CagA status in dyspeptic patients.” Helicobacter. 2001 Jun;6(2):130-553. Boirivant M, Pica R, DeMaria R, Testi R, Pallone F, Strober W. “Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis.” J Clin Invest. 1996 Dec 1;98(11):2616-22